Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559526 | 0.91 | CCR6 (0.53) | LMNASMN1; SMN2CCR6PAX8L3MBTL1 | |
| SCHEMBL25344783 | 0.91 | SYK (0.47) | LMNASMN1; SMN2CCR6PAX8L3MBTL1 | |
| SCHEMBL15055271 | 0.89 | CCR6 (0.51) | LMNASMN1; SMN2CCR6PAX8L3MBTL1 | |
| SCHEMBL15841146 | 0.88 | CCR6 (0.50) | LMNACCR6PAX8L3MBTL1MAPT | |
| SCHEMBL6770668 | 0.85 | ALDH1A1 (0.43) | HTTMAPTTGM2 | |
| SCHEMBL13661453 | 0.84 | CCR6 (0.47) | LMNACCR6PAX8L3MBTL1MAPT | |
| SCHEMBL27483085 | 0.84 | CCR6 (0.47) | LMNASMN1; SMN2CCR6PAX8CA12 | |
| SCHEMBL3524616 | 0.84 | LMNA (0.68) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL2453446 | 0.83 | HTT (0.60) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL4280634 | 0.83 | PTGDR2 (0.46) | LMNACCR6PAX8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151165-C | Macrolides with anti-inflammatory activity | �ź㴫 | 2004-05-26 | — | — | CN | disclosed |
| CN-1336932-A | Macrolides with anti-inflammatory activity | ZAMBON SPA (IT) | 2002-02-20 | — | — | CN | disclosed |