Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 4/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316158 | 0.91 | MAPT (0.63) | MAPTTDP1POLBL3MBTL1KDM4E | |
| SCHEMBL3196199 | 0.89 | MAPT (0.70) | MAPTTDP1POLBL3MBTL1KDM4E | |
| SCHEMBL6053977 | 0.81 | MAPT (0.66) | MAPTTDP1POLBL3MBTL1KDM4E | |
| SCHEMBL744521 | 0.81 | MAPT (0.66) | MAPTTDP1POLBL3MBTL1KDM4E | |
| SCHEMBL9401906 | 0.81 | MAPT (0.61) | MAPTTDP1POLBL3MBTL1KDM4E | |
| SCHEMBL20176812 | 0.81 | MAPT (0.61) | MAPTTDP1POLBL3MBTL1KDM4E | |
| SCHEMBL9401911 | 0.81 | MAPT (0.61) | MAPTTDP1POLBL3MBTL1KDM4E | |
| SCHEMBL12358254 | 0.79 | MAPT (0.58) | MAPTTDP1POLBL3MBTL1KDM4E | |
| SCHEMBL24691595 | 0.78 | MAPT (0.57) | MAPTTDP1POLBL3MBTL1KDM4E | |
| SCHEMBL10377521 | 0.78 | TDP1 (0.63) | MAPTTDP1POLBL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116287032-A | Method for preparing 3-oxo-ethyl butyrate derivative by reacting aromatic aldehyde with ethyl acetoacetate under enzyme catalysis | 岭南师范学院 | 2023-06-23 | — | — | CN | disclosed |
| CN-1083474-A | The preparation of dihydrogen pyridine derivative | MEI QIBING (CN) | 1994-03-09 | — | — | CN | disclosed |