SCHEMBL3196199

SCHEMBL3196199

O=C(O)C(=Cc1ccco1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.70
POLB P06746 3/20 0.70
TDP1 Q9NUW8 2/20 0.70
L3MBTL1 Q9Y468 2/20 0.70
KDM4E B2RXH2 2/20 0.70
KMT2A Q03164 3/20 0.62
TSHR P16473 1/20 0.62
CYP2C19 P33261 1/20 0.62
MEN1 O00255 2/20 0.61
HCAR2 Q8TDS4 1/20 0.55
ALDH1A1 P00352 2/20 0.50
MASP2 O00187 1/20 0.50
F2 P00734 1/20 0.50
GAA P10253 1/20 0.46
PTPN1 P18031 1/20 0.45
LMNA P02545 1/20 0.44
PKM P14618 1/20 0.44
PLA2G7 Q13093 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27465110 0.89 MAPT (0.71) MAPTPOLBTDP1L3MBTL1KDM4E
SCHEMBL4729615 0.82 MAPT (0.80) MAPTPOLBTDP1L3MBTL1KDM4E
SCHEMBL9316158 0.82 MAPT (0.63) MAPTPOLBTDP1L3MBTL1KDM4E
SCHEMBL27852160 0.81 TDP1 (0.63) MAPTPOLBTDP1L3MBTL1KDM4E
SCHEMBL24691595 0.81 MAPT (0.57) MAPTPOLBTDP1L3MBTL1KDM4E
SCHEMBL744521 0.80 MAPT (0.66) MAPTPOLBTDP1L3MBTL1KDM4E
SCHEMBL9131681 0.80 KMT2A (0.59) MAPTPOLBTDP1L3MBTL1KDM4E
SCHEMBL6053977 0.80 MAPT (0.66) MAPTPOLBTDP1L3MBTL1KDM4E
SCHEMBL9131685 0.80 KMT2A (0.59) MAPTPOLBTDP1L3MBTL1KDM4E
SCHEMBL11074738 0.79 KMT2A (0.57) MAPTPOLBTDP1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236972-B2 Reacting biomass-derived furfural and malonic acid using basic catalysts to form a Knoevenagel product such as 2-(furan-2-ylmethylene)malonic acid, followed by hydrodeoxygenation to branched alkanes, or branched alkene product; biogasoline; cost efficiency GEORGIA TECH RESEARCH CORPORATION (US) 2012-08-07 US claimed
US-20100029926-A1 MOLECULAR MASS ENHANCEMENT OF BIOLOGICAL FEEDSTOCKS GEORGIA TECH RESEARCH CORPORATION (US) 2010-02-04 US claimed
JP-2007502314-A 2007-02-08 JP claimed
US-20070010579-A1 Copper salts of organic acids and use thereof as fungicides ISARGO S.P.A. (IT) 2007-01-11 US claimed
EP-1633190-A1 COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES ISAGRO S.p.A. (IT) 2006-03-15 EP claimed
WO-2004103074-A1 COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES ISAGRO S.P.A. (IT) 2004-12-02 WO claimed
EP-0361205-B1 Plastoelastomeric polyolefin compositions and process for preparing them HIMONT ITALIA (IT) 1995-05-10 EP claimed
EP-0361205-A2 Plastoelastomeric polyolefin compositions and process for preparing them HIMONT ITALIA S.r.l. (IT) 1990-04-04 EP claimed
US-20250051687-A1 MALONATE AND FURAN BASED SURFACTANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2025-02-13 US disclosed
EP-4433465-A1 MALONATE AND FURAN BASED SURFACTANTS Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO (NL) 2024-09-25 EP disclosed
WO-2023091017-A1 MALONATE AND FURAN BASED SURFACTANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2023-05-25 WO disclosed
EP-4183779-A1 MALONATE AND FURAN BASED SURFACTANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2023-05-24 EP disclosed
US-10561594-B2 Agent for stabilizing keratin fibers with 5-ring heterocycles HENKEL AG & CO. KGAA (DE) 2020-02-18 US disclosed
US-20180140525-A1 AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES HENKEL AG & CO. KGAA (DE) 2018-05-24 US disclosed
EP-0361205-B1 Plastoelastomeric polyolefin compositions and process for preparing them HIMONT ITALIA (IT) 1995-05-10 EP disclosed
US-5082869-A Homogeneous, flexible AUSIMONT S.P.A. (IT) 1992-01-21 US disclosed
US-5066700-A Organic Peroxide Vulcanizing Agent, Furan Derivative As A Crosslinking Coadjuvant AUSIMONT S.P.A. (IT) 1991-11-19 US disclosed
EP-0450342-A2 Crosslinked polypropylene compositions suitable for the manufacture of foamed articles SPHERILENE S.r.l. (IT) 1991-10-09 EP disclosed
US-4963612-A Plastoelastomeric polyolefinic compositions and process for preparing them according to dynamic vulcanizable methods AUSIMONT S.R.L. (IT) 1990-10-16 US disclosed
EP-0361205-A2 Plastoelastomeric polyolefin compositions and process for preparing them HIMONT ITALIA S.r.l. (IT) 1990-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180140525-A1 AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES KRT18, NDUFS5, NDUFA5 MAPT 1624/4885POLB 1895/4885TDP1 4143/4885
US-20070010579-A1 Copper salts of organic acids and use thereof as fungicides AOC3, AOC2, AOC1 MAPT 679/4885POLB 3257/4885TDP1 2559/4885
US-10561594-B2 Agent for stabilizing keratin fibers with 5-ring heterocycles KRT18, NDUFS5, NDUFA5 MAPT 1624/4885POLB 1895/4885TDP1 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.