Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943038 | 0.90 | ALDH1A1 (0.48) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL11223652 | 0.86 | TSHR (0.58) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL26685101 | 0.85 | TSHR (0.51) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL29198318 | 0.84 | TSHR (0.47) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL28668751 | 0.83 | TSHR (0.44) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL6444011 | 0.82 | TSHR (0.43) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL27465283 | 0.82 | TSHR (0.52) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL27875169 | 0.82 | TSHR (0.47) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL22187020 | 0.81 | TSHR (0.42) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL28030632 | 0.81 | TSHR (0.55) | TSHRTHRBALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146909-A2 | OPTICAL BRIGHTER AND UV STABILIZER FOR ACRYLIC ENHANCEMENTS | ESSCHEM, INC. (US) | 2007-12-21 | — | — | WO | disclosed |