Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467638 | 0.85 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL27482765 | 0.84 | MEN1 (0.50) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27483477 | 0.74 | KDM4E (0.41) | SLC6A3ALDH1A1EPHX2 | |
| SCHEMBL27483137 | 0.74 | KMT2A (0.38) | SLC6A3SLC6A2ALDH1A1 | |
| SCHEMBL27482391 | 0.73 | SLC6A3 (0.48) | SLC6A3ALDH1A1 | |
| SCHEMBL27865159 | 0.71 | KMT2A (0.53) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2646035 | 0.70 | EPHX2 (0.45) | SLC6A3SLC6A2SLC6A4L3MBTL1ALDH1A1 | |
| SCHEMBL25022001 | 0.70 | PYGL (0.35) | L3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL11548405 | 0.70 | KMT2A (0.55) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2646806 | 0.69 | MEN1 (0.43) | SLC6A3SLC6A2SLC6A4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |