Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467638 | 0.86 | SLC6A3 (0.48) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27865159 | 0.85 | KMT2A (0.53) | MEN1KMT2ASLC6A3SLC6A2CYP3A4 | |
| SCHEMBL27465658 | 0.84 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11548405 | 0.84 | KMT2A (0.55) | MEN1KMT2ASLC6A3SLC6A2CYP3A4 | |
| SCHEMBL27483137 | 0.83 | KMT2A (0.38) | MEN1KMT2ASLC6A3SLC6A2CHRM2 | |
| SCHEMBL27483477 | 0.83 | KDM4E (0.41) | MEN1KMT2ASLC6A3 | |
| SCHEMBL27482391 | 0.82 | SLC6A3 (0.48) | MEN1KMT2ASLC6A3LMNA | |
| SCHEMBL27407428 | 0.80 | TSHR (0.50) | MEN1KMT2ASLC6A3SLC6A2CYP3A4 | |
| SCHEMBL27661415 | 0.79 | PKM (0.57) | MEN1KMT2ASLC6A3SLC6A2CYP3A4 | |
| SCHEMBL29706736 | 0.79 | MEN1 (0.52) | MEN1KMT2ASLC6A3SLC6A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |