Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15034733 | 0.82 | KIF11 (0.67) | KIF11KDM4EALDH1A1AHRGABRA1 | |
| SCHEMBL1648901 | 0.77 | KDM4E (0.74) | KIF11KDM4EALDH1A1MAPTIMPDH2 | |
| SCHEMBL10442374 | 0.77 | KDM4E (0.53) | KIF11KDM4EALDH1A1MAPTIMPDH2 | |
| SCHEMBL278610 | 0.76 | KIF11 (1.00) | KIF11KDM4EALDH1A1MAPTMEN1 | |
| Methane SCHEMBL8206725 | 0.76 | KDM4E (0.72) | KIF11KDM4EALDH1A1MAPTIMPDH2 | |
| SCHEMBL498758 | 0.75 | PTGS2 (0.70) | KIF11MAPTPDPK1IMPDH2MEN1 | |
| SCHEMBL30927850 | 0.75 | KDM4E (0.61) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30419824 | 0.75 | KDM4E (0.61) | KIF11KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29760781 | 0.75 | PTGS2 (0.70) | KIF11MAPTPDPK1IMPDH2MEN1 | |
| SCHEMBL12154974 | 0.74 | SLC7A5 (0.54) | KIF11KDM4EALDH1A1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138764-C | Isoxazole derivatives | ס����ҩ��ʽ���� | 2004-02-18 | — | — | CN | disclosed |
| CN-1252794-A | Isoxazole derivatives | SUMITOMO PHARMA (JP) | 2000-05-10 | — | — | CN | disclosed |