Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | C5 | P01031 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | KIF11 | P52732 | 4/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29760781 | 1.00 | PTGS2 (0.70) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL12286224 | 0.91 | KIF11 (0.66) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL11067278 | 0.91 | KMT2A (0.66) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL31324175 | 0.86 | PTGS2 (0.68) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL11298149 | 0.84 | KIF11 (0.60) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL9138943 | 0.84 | PTGS2 (0.73) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL8189543 | 0.84 | KIF11 (0.60) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL7517221 | 0.83 | KIF11 (0.58) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL6072669 | 0.82 | KIF11 (0.59) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| Carprofen SCHEMBL3909 | 0.82 | PTGS2 (1.00) | PTGS2MEN1PTGS1KMT2AABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112526038-B | Carprofen and related substance detection method | 河北科技大学 | 2022-07-12 | — | — | CN | claimed |
| CN-112526038-A | Carprofen and related substance detection method | 河北科技大学 | 2021-03-19 | — | — | CN | claimed |
| US-20050232957-A1 | Compositions and methods for moisturizing skin | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 2005-10-20 | — | — | US | claimed |
| CN-112526038-B | Carprofen and related substance detection method | 河北科技大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-113636965-A | High penetration composition and application thereof | 于崇曦 | 2021-11-12 | — | — | CN | disclosed |
| CN-107320732-B | High penetration composition and application thereof | 于崇曦 | 2021-09-07 | — | — | CN | disclosed |
| CN-108191846-B | High penetration composition and application thereof | 于崇曦 | 2021-08-20 | — | — | CN | disclosed |
| CN-112526038-A | Carprofen and related substance detection method | 河北科技大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-111808011-A | High penetration composition and application thereof | 于崇曦 | 2020-10-23 | — | — | CN | disclosed |
| EP-2379109-B1 | COMBINATION OF PHOTODYNAMIC THERAPY AND ANTI-VEGF AGENTS IN THE TREATMENT OF UNWANTED CHOROIDAL NEOVASCULATURE | BAUSCH HEALTH COMPANIES INC (CA) | 2020-10-07 | — | — | EP | disclosed |
| US-9226917-B2 | Photodynamic therapy for conditions of the eye | VALEANT PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| WO-2001035996-A2 | USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA | QLT INC. (CA) | 2001-05-25 | — | — | WO | disclosed |
| EP-0988034-A1 | COX-2 SELECTIVE CARPROFEN FOR TREATING PAIN AND INFLAMMATION IN DOGS | PFIZER INC. (US) | 2000-03-29 | — | — | EP | disclosed |
| EP-0151423-A2 | Process for the preparation of a carbazole derivative | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-08-14 | — | — | EP | disclosed |
| US-4226774-A | Carbazole melonates | HOFFMANN-LA ROCHE INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4226774-A | Carbazole melonates | HOFFMANN-LA ROCHE INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4193923-A | Tetrahydro 2-carbazolyl methyl malonate derivatives | HOFFMANN-LA ROCHE INC. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4193923-A | Tetrahydro 2-carbazolyl methyl malonate derivatives | HOFFMANN-LA ROCHE INC. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4158007-A | Carbazole methyl malonates | HOFFMANN-LA ROCHE INC. (US) | 1979-06-12 | — | — | US | disclosed |
| US-4158007-A | Carbazole methyl malonates | HOFFMANN-LA ROCHE INC. (US) | 1979-06-12 | — | — | US | disclosed |