Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466722 | 0.79 | HDAC8 (0.48) | HDAC8HDAC6HDAC1 | |
| SCHEMBL27482758 | 0.78 | MDM2 (0.41) | ALDH1A1MDM2HDAC8HDAC6HDAC1 | |
| SCHEMBL27466734 | 0.77 | HDAC8 (0.38) | HDAC8HDAC6HDAC1 | |
| SCHEMBL27466733 | 0.77 | HDAC8 (0.38) | HDAC8HDAC6HDAC1 | |
| SCHEMBL27480883 | 0.74 | HDAC8 (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL27466726 | 0.73 | KMT2A (0.44) | KMT2AMEN1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL27466732 | 0.71 | HDAC8 (0.41) | HDAC8HDAC6HDAC1 | |
| SCHEMBL27504948 | 0.71 | HDAC8 (0.38) | HDAC8HDAC6HDAC1L3MBTL1 | |
| SCHEMBL9513694 | 0.69 | VCAM1 (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL731001 | 0.68 | IDO1 (0.62) | MAPTALDH1A1LMNAVCAM1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |