Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27354731 | 0.91 | — | — | |
| SCHEMBL4873522 | 0.90 | DNM1 (0.46) | DNM1TSHRALDH1A1CA12CA1 | |
| SCHEMBL28033734 | 0.89 | ADRB2 (0.39) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL9766741 | 0.84 | DNM1 (0.40) | DNM1TSHRALDH1A1CA12CA1 | |
| SCHEMBL5548355 | 0.82 | — | — | |
| SCHEMBL4791083 | 0.81 | DNM1 (0.42) | DNM1TSHRALDH1A1CA12CA1 | |
| SCHEMBL2216829 | 0.80 | ALDH1A1 (0.43) | TSHRLMNAALDH1A1ALDH2CA12 | |
| SCHEMBL28121801 | 0.80 | DNM1 (0.33) | DNM1TSHRLMNAALDH1A1ALDH2 | |
| SCHEMBL6679948 | 0.79 | DNM1 (0.46) | DNM1TSHRALDH1A1CA12CA1 | |
| SCHEMBL27753993 | 0.76 | DNM1 (0.31) | DNM1TSHRLMNAALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106265598-A | A kind of based on biological functionalized nano silver paclitaxel loaded or the targeted delivery systems of its analog | 广东工业大学 | 2017-01-04 | — | — | CN | claimed |
| CN-105452232-A | Process for the preparation of dronedarone and salts thereof | GILEAD SCIENCES INC | 2016-03-30 | — | — | CN | claimed |
| CN-104220413-B | Method for producing 4-hydroxybutyl acrylate | 大阪有机化学工业株式会社 | 2018-12-04 | — | — | CN | disclosed |
| CN-105339341-B | Production system for (meth) acrylic acid ester | 大阪有机化学工业株式会社 | 2018-02-13 | — | — | CN | disclosed |
| CN-107540565-A | The preparation of N, N (two) alkyl amino alkyl (methyl) acrylamide or corresponding ester and its quaternary ammonium salt | 赢创罗姆有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-106265598-A | A kind of based on biological functionalized nano silver paclitaxel loaded or the targeted delivery systems of its analog | 广东工业大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-105452232-A | Process for the preparation of dronedarone and salts thereof | GILEAD SCIENCES INC | 2016-03-30 | — | — | CN | disclosed |
| CN-105339341-A | Production system for (meth) acrylic acid ester | OSAKA ORGANIC CHEM IND | 2016-02-17 | — | — | CN | disclosed |
| CN-104220413-A | Method for producing 4-hydroxybutyl acrylate | OSAKA ORGANIC CHEM IND | 2014-12-17 | — | — | CN | disclosed |
| CN-1156961-A | Formulations and method for providing prolonged local anesthesia | EURO CELTIQUE SA (LU) | 1997-08-13 | — | — | CN | disclosed |