Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 8/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPX4 | P36969 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450674 | 0.83 | SLC6A3 (0.40) | SLC6A3FFAR2CTSAMEN1LMNA | |
| SCHEMBL1500596 | 0.79 | CYP2D6 (0.52) | SLC6A3GPX4CYP2D6CYP19A1CHRM2 | |
| Bromide SCHEMBL1782497 | 0.77 | CYP2D6 (0.50) | SLC6A3GPX4CYP2D6CYP19A1CHRM2 | |
| Hydrochloric Acid SCHEMBL1782142 | 0.77 | CYP2D6 (0.50) | SLC6A3MEN1LMNAKMT2AGPX4 | |
| SCHEMBL3298937 | 0.75 | OPRM1 (0.44) | SLC6A3MEN1LMNAKMT2AKDM4E | |
| SCHEMBL1779185 | 0.73 | CYP2D6 (0.46) | SLC6A3GPX4CYP2D6CYP19A1CHRM2 | |
| SCHEMBL6011470 | 0.71 | FFAR2 (0.46) | SLC6A3FFAR2CTSAMEN1LMNA | |
| SCHEMBL5078319 | 0.70 | CTSA (0.39) | SLC6A3FFAR2CTSAMEN1LMNA | |
| SCHEMBL5078943 | 0.70 | CTSA (0.39) | SLC6A3FFAR2CTSAMEN1LMNA | |
| SCHEMBL5075741 | 0.70 | CTSA (0.39) | SLC6A3FFAR2CTSAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149191-C | Azetidine derivatives, Preparation and medicines containing them | ���ĵ�˹ҩ��ɷ�����˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1316991-A | Azetidine derivatives, preparation and medicines containing them | AVENTIS PHARMA SA (FR) | 2001-10-10 | — | — | CN | disclosed |