Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28287263 | 0.92 | IKBKB (0.47) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL3266308 | 0.88 | LMNA (0.60) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL6042801 | 0.86 | PTPN1 (0.51) | LMNAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL353286 | 0.84 | MAPT (0.48) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL6290060 | 0.83 | TBXAS1 (0.39) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL6042670 | 0.81 | BRD4 (0.52) | MAPTKMT2APTPN1KDM4EGAA | |
| SCHEMBL29941277 | 0.81 | MKNK1 (0.48) | LMNAMEN1KMT2AKDM4EGAA | |
| SCHEMBL6305012 | 0.81 | MKNK1 (0.48) | LMNAMEN1KMT2AKDM4EGAA | |
| SCHEMBL29503858 | 0.80 | PLAU (0.53) | LMNAMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL1101140 | 0.80 | PLAU (0.53) | LMNAMEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1136556-A | Aromatic group substituted W-amino alkyl amide and alkyl amide | CIBA GEIGY CO LTD (CH) | 1996-11-27 | — | — | CN | disclosed |