Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353286 | 0.91 | MAPT (0.48) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL27466976 | 0.88 | LMNA (0.46) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL27480442 | 0.86 | PTPN1 (0.60) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| Zinc Ion SCHEMBL9440333 | 0.85 | PTPN1 (0.54) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL8882025 | 0.85 | PTPN1 (0.62) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL29941277 | 0.84 | MKNK1 (0.48) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6305012 | 0.84 | MKNK1 (0.48) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2271444 | 0.84 | PTPN1 (0.61) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL28287263 | 0.83 | IKBKB (0.47) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL6290060 | 0.83 | TBXAS1 (0.39) | LMNAMEN1NR1I2CHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7692020-B2 | Process for the preparation of pyridylcarboxylic amides and esters | BASF SE (DE) | 2010-04-06 | — | — | US | claimed |
| EP-1948609-B1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2010-03-10 | — | — | EP | claimed |
| US-20080249313-A1 | Process for the Preparation of Pyridylcarboxylic Amides and Esters | BASF SE (DE) | 2008-10-09 | — | — | US | claimed |
| EP-1948609-A1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2008-07-30 | — | — | EP | claimed |
| WO-2007051759-A1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2007-05-10 | — | — | WO | claimed |
| US-7692020-B2 | Process for the preparation of pyridylcarboxylic amides and esters | BASF SE (DE) | 2010-04-06 | — | — | US | disclosed |
| EP-1948609-B1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |
| US-20080249313-A1 | Process for the Preparation of Pyridylcarboxylic Amides and Esters | BASF SE (DE) | 2008-10-09 | — | — | US | disclosed |
| EP-1948609-A1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007051759-A1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249313-A1 | Process for the Preparation of Pyridylcarboxylic Amides and Esters | ADH1C, ADH1A, CBR1 | LMNA 2011/4885MEN1 3927/4885NR1I2 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.