Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | FASN | P49327 | 2/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468183 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL27468184 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL27467282 | 0.90 | ALDH1A1 (0.44) | ALDH1A1CYP2C19KDM4EPOLBHPGD | |
| SCHEMBL27468375 | 0.90 | ALDH1A1 (0.44) | ALDH1A1CYP2C19KDM4EPOLBHPGD | |
| SCHEMBL27468377 | 0.90 | ALDH1A1 (0.44) | ALDH1A1CYP2C19KDM4EPOLBHPGD | |
| SCHEMBL27466997 | 0.83 | ITGB3 (0.40) | ALDH1A1CYP2C19HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL27467921 | 0.83 | ITGB3 (0.40) | ALDH1A1CYP2C19HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL27467918 | 0.83 | ITGB3 (0.40) | ALDH1A1CYP2C19HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL27467467 | 0.82 | CYP3A4 (0.40) | HSD17B10 | |
| SCHEMBL27468603 | 0.82 | CYP3A4 (0.40) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |