Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467282 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27468377 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27468184 | 0.90 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27467166 | 0.90 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27468183 | 0.90 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL27467918 | 0.85 | ITGB3 (0.40) | ALDH1A1HPGDSMN1; SMN2HSD17B10ITGB3 | |
| SCHEMBL27467921 | 0.85 | ITGB3 (0.40) | ALDH1A1HPGDSMN1; SMN2HSD17B10ITGB3 | |
| SCHEMBL27466997 | 0.85 | ITGB3 (0.40) | ALDH1A1HPGDSMN1; SMN2HSD17B10ITGB3 | |
| SCHEMBL27467468 | 0.84 | ITGB3 (0.38) | ALDH1A1KDM4EPOLBITGB3ITGA2B | |
| SCHEMBL27468608 | 0.84 | ITGB3 (0.38) | ALDH1A1KDM4EPOLBITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |