Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481116 | 0.85 | TBXAS1 (0.54) | CYP19A1TBXAS1AGTR2CYP11B1CYP11B2 | |
| SCHEMBL2651961 | 0.75 | ALDH1A1 (0.51) | CYP19A1ALDH1A1CYP11B1CYP11B2LMNA | |
| SCHEMBL9853963 | 0.75 | CYP19A1 (0.80) | CYP19A1TBXAS1AGTR2CYP11B1CYP11B2 | |
| SCHEMBL27467900 | 0.73 | SERPINE1 (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL23978310 | 0.72 | MAPT (0.57) | ALDH1A1LMNA | |
| SCHEMBL9665076 | 0.71 | ALDH1A1 (0.61) | CYP19A1TBXAS1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL10580633 | 0.71 | CYP19A1 (0.58) | CYP19A1TBXAS1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL10578330 | 0.71 | CYP19A1 (0.61) | CYP19A1TBXAS1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL6005065 | 0.71 | MEN1 (0.52) | CYP19A1TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL2652140 | 0.70 | CYP19A1 (0.44) | CYP19A1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167686-C | Novel benzimidazole derivatives and pharmaceutical compsns. comprising these compounds | О | 2004-09-22 | — | — | CN | disclosed |
| CN-1356987-A | Novel benzimidazole derivatives and pharmaceutical compsns. comprising these compounds | NEUROSEARCH AS (DK) | 2002-07-03 | — | — | CN | disclosed |