Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744350 | 0.85 | HTR2A (0.33) | — | |
| SCHEMBL27465296 | 0.82 | BRD4 (0.40) | BRD4MEN1KMT2ALMNA | |
| SCHEMBL27480961 | 0.77 | PGR (0.40) | — | |
| SCHEMBL27578086 | 0.77 | PDPK1 (0.33) | — | |
| SCHEMBL27481361 | 0.76 | PGR (0.41) | BRD4 | |
| SCHEMBL27481747 | 0.74 | ALDH1A1 (0.34) | BRD4MEN1KMT2ALMNAPMP22 | |
| SCHEMBL27481748 | 0.72 | BRD4 (0.47) | BRD4KMT2ALMNA | |
| SCHEMBL23497996 | 0.70 | TSHR (0.32) | LMNAPMP22NPSR1GFER | |
| SCHEMBL29744432 | 0.70 | TSHR (0.32) | LMNAPMP22NPSR1GFER | |
| SCHEMBL6541587 | 0.69 | KMT2A (0.51) | BRD4MEN1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201820-C | Compositions containing benzimidazolones and progestogens | WYETH CORP (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1152020-C | Benzimidazolrone and analogues, and the use as ligand of progesterone | �Ʒ� | 2004-06-02 | — | — | CN | disclosed |
| CN-1349511-A | Benzimidazolrone and analogues, and the use as ligand of progesterone | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1349411-A | Compositions containing benzimidazolones and progestogens | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |