SCHEMBL27465296

SCHEMBL27465296

CN1CC(C=O)Nc2ccc(Br)cc21

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALOX5 P09917 1/20 0.31
LMNA P02545 1/20 0.30
PKM P14618 1/20 0.30
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27468217 0.82 BRD4 (0.32) BRD4MEN1KMT2ALMNA
SCHEMBL27481747 0.80 ALDH1A1 (0.34) BRD4MEN1KMT2ALMNA
SCHEMBL29007525 0.79 CYP11B1 (0.38) BRD4MEN1KMT2A
SCHEMBL27481748 0.75 BRD4 (0.47) BRD4KMT2ALMNA
SCHEMBL27527843 0.75 PGR (0.42)
SCHEMBL28937477 0.72 ADRA2A (0.36) BRD4MEN1KMT2AALOX5LMNA
SCHEMBL27465790 0.72 PGR (0.46)
SCHEMBL22471500 0.70 BRD4 (0.38) BRD4
SCHEMBL27740237 0.69 CMA1 (0.34) BRD4MEN1KMT2A
SCHEMBL28787427 0.68 SNCA (0.34) BRD4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1201820-C Compositions containing benzimidazolones and progestogens WYETH CORP (US) 2005-05-18 CN disclosed
CN-1152020-C Benzimidazolrone and analogues, and the use as ligand of progesterone �Ʒ� 2004-06-02 CN disclosed
CN-1349511-A Benzimidazolrone and analogues, and the use as ligand of progesterone AMERICAN HOME PROD (US) 2002-05-15 CN disclosed
CN-1349411-A Compositions containing benzimidazolones and progestogens AMERICAN HOME PROD (US) 2002-05-15 CN disclosed