Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 4/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL15772805 | 0.89 | KMT2A (0.37) | GABRA1GABRB2METAP2KDM4EKMT2A | |
| Malic Acid SCHEMBL28420688 | 0.81 | SMN1; SMN2 (0.43) | CDC7DBF4METAP2 | |
| SCHEMBL27483211 | 0.78 | NOS2 (0.44) | GABRA1GABRB2NOS3NOS2NOS1 | |
| SCHEMBL3801869 | 0.77 | NOS2 (0.38) | GABRA1GABRB2NOS3NOS2NOS1 | |
| SCHEMBL13180249 | 0.77 | GABRA1 (0.37) | GABRA1GABRB2NOS3NOS2NOS1 | |
| SCHEMBL12309822 | 0.76 | PDE3B (0.42) | NOS3NOS2NOS1METAP2KDM4E | |
| SCHEMBL23193106 | 0.74 | GABRA1 (0.48) | GABRA1GABRB2NOS3NOS2KDM4E | |
| SCHEMBL11965050 | 0.74 | FFAR1 (0.37) | NOS3NOS2NOS1KDM4ELMNA | |
| SCHEMBL9127089 | 0.74 | NOS3 (0.35) | NOS3NOS2NOS1METAP2 | |
| SCHEMBL10202135 | 0.74 | FFAR1 (0.37) | NOS3NOS2NOS1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1535958-A | Alpha-substituted pyrimidine. thioalkyl and alkyl ether compound | �������Ŷ���Լ��������˾ | 2004-10-13 | — | — | CN | disclosed |
| CN-1152022-C | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds | �������Ŷ���Լ��������˾ | 2004-06-02 | — | — | CN | disclosed |
| CN-1183773-A | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds | UPJOHN CO (US) | 1998-06-03 | — | — | CN | disclosed |