SCHEMBL27468464

SCHEMBL27468464

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nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
PTPN1 P18031 1/20 0.40
PDE4A P27815 1/20 0.39
USP2 O75604 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
KDM4E B2RXH2 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29886751 1.00 LMNA (0.46) LMNAL3MBTL1TDP1PTPN1PDE4A
SCHEMBL29408337 0.94 LMNA (0.42) LMNAL3MBTL1TDP1PTPN1PDE4A
SCHEMBL29431969 0.94 LMNA (0.42) LMNAL3MBTL1TDP1PTPN1PDE4A
SCHEMBL8854308 0.87 PTPN1 (0.41) TDP1PTPN1
SCHEMBL29919554 0.86 LMNA (0.41) LMNAL3MBTL1TDP1PTPN1PDE4A
SCHEMBL28033517 0.85 PTPN1 (0.43) LMNAL3MBTL1TDP1PTPN1
SCHEMBL2216482 0.85 PTPN1 (0.43) LMNAL3MBTL1TDP1PTPN1
SCHEMBL13636541 0.79 PTPN1 (0.33) PTPN1
SCHEMBL31355180 0.79 LMNA (0.40) LMNAL3MBTL1TDP1PTPN1PDE4A
SCHEMBL1462510 0.79 TDP1 (0.50) LMNAL3MBTL1TDP1PTPN1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1167113-A Phosphate alkyl ester or phosphate acyl dihydration 1,4:3,6-D-gluconic alcohol ester and preparing method and application CECA SA (FR) 1997-12-10 CN disclosed