SCHEMBL29408337

SCHEMBL29408337

O=P(O)(O)O[C@@H](CO)[C@@H](O)[C@H](O)CO

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PTPN1 P18031 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
PDE4A P27815 1/20 0.35
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
MPI P34949 1/20 0.31
PGD P52209 1/20 0.31
KDM4E B2RXH2 2/20 0.31
SMPD1 P17405 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431969 1.00 LMNA (0.42) LMNAL3MBTL1PTPN1TDP1PDE4A
SCHEMBL27468464 0.94 LMNA (0.46) LMNAL3MBTL1PTPN1TDP1PDE4A
SCHEMBL29886751 0.94 LMNA (0.46) LMNAL3MBTL1PTPN1TDP1PDE4A
SCHEMBL8854308 0.89 PTPN1 (0.41) PTPN1TDP1MPIPGDSMPD1
SCHEMBL28033517 0.86 PTPN1 (0.43) LMNAL3MBTL1PTPN1TDP1MPI
SCHEMBL2216482 0.86 PTPN1 (0.43) LMNAL3MBTL1PTPN1TDP1MPI
SCHEMBL1921547 0.83 PTPN1 (0.36) LMNAL3MBTL1PTPN1TDP1PDE4A
SCHEMBL3507130 0.83 PTPN1 (0.36) LMNAL3MBTL1PTPN1TDP1PDE4A
SCHEMBL3507128 0.83 PTPN1 (0.36) LMNAL3MBTL1PTPN1TDP1PDE4A
SCHEMBL5789757 0.83 PTPN1 (0.36) LMNAL3MBTL1PTPN1TDP1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130930-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING RESPIRATORY RELATED DISEASES AND CONDITIONS WITH XYLITOL-HEADGROUP LIPID ANALOGS NAT JEWISH HEALTH (US) 2026-05-14 US disclosed
US-12472193-B2 Methods and compositions for treating and preventing respiratory related diseases and conditions with xylitol-headgroup lipid analogs NATIONAL JEWISH HEALTH (US) 2025-11-18 US disclosed
US-20240277737-A1 METHOD FOR GENERATING DRY POWDER SUITABLE FOR INHALATION ADMINISTRATION OF ANTIMICROBIAL PHOSPHOLIPID COMPOSITIONS CELESTIAL THERAPEUTICS, INC. 2024-08-22 US disclosed
WO-2023028354-A1 METHOD FOR GENERATING DRY POWDER SUITABLE FOR INHALATION/INTRANASAL/INTRATRACHEAL ADMINISTRATION OF ANTIMICROBIAL PHOSPHOLIPID COMPOSITIONS CELESTIAL THERAPEUTICS, INC (US) 2023-03-02 WO disclosed
US-20220273681-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING RESPIRATORY RELATED DISEASES AND CONDITIONS WITH XYLITOL-HEADGROUP LIPID ANALOGS NATIONAL JEWISH HEALTH 2022-09-01 US disclosed
US-11278556-B2 Methods and compositions for treating and preventing respiratory related diseases and conditions with xylitol-headgroup lipid analogs NATIONAL JEWISH HEALTH (US) 2022-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130930-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING RESPIRATORY RELATED DISEASES AND CONDITIONS WITH XYLITOL-HEADGROUP LIPID ANALOGS PCTP, SGMS1, PHOSPHO1 LMNA 683/4885L3MBTL1 3403/4885PTPN1 590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.