Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456712 | 0.83 | TDP1 (0.41) | GAASMN1; SMN2PKMTDP1MEN1 | |
| SCHEMBL12800195 | 0.81 | TDP1 (0.46) | GAASMN1; SMN2PKMTDP1MEN1 | |
| Dimethylformamide SCHEMBL27912979 | 0.81 | HCAR3 (0.36) | SMN1; SMN2TDP1ALDH1A1LMNA | |
| SCHEMBL7454078 | 0.79 | TDP1 (0.47) | GAASMN1; SMN2PKMTDP1MEN1 | |
| SCHEMBL7455786 | 0.77 | ALDH1A1 (0.48) | GAASMN1; SMN2PKMTDP1MEN1 | |
| SCHEMBL27468547 | 0.75 | SMN1; SMN2 (0.49) | GAASMN1; SMN2PKMMEN1KMT2A | |
| Dimethylformamide SCHEMBL27895443 | 0.74 | L3MBTL1 (0.42) | GAASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL28534811 | 0.74 | SMN1; SMN2 (0.64) | GAASMN1; SMN2PKMTDP1MEN1 | |
| SCHEMBL10775005 | 0.74 | SMN1; SMN2 (0.48) | GAASMN1; SMN2PKMMEN1KMT2A | |
| SCHEMBL15882234 | 0.72 | VCAM1 (0.39) | GAASMN1; SMN2PKMTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947292-A | nitrogen-containing heteroaryl compounds | HOFFMANN LA ROCHE | 2013-02-27 | — | — | CN | disclosed |