Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | ACR | P10323 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404224 | 0.85 | EGFR (0.57) | MAPTGRM5EGFRPTGS2NEK1 | |
| SCHEMBL7823524 | 0.78 | RAB9A (0.48) | MAPTGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7752770 | 0.77 | PRSS1 (0.66) | MAPTTDP1PRSS1ACRESR1 | |
| SCHEMBL1330582 | 0.77 | KDM4E (0.52) | GRM5EGFRGABRG2GABRB3GABRA5 | |
| SCHEMBL8155327 | 0.77 | PTGS2 (0.54) | MAPTGRM5EGFRPTGS2NEK1 | |
| SCHEMBL28577777 | 0.76 | EGFR (0.52) | MAPTTDP1GRM5EGFRPTGS2 | |
| SCHEMBL10630065 | 0.76 | TSHR (0.62) | MAPTTDP1PRSS1ACRGABRG2 | |
| Hydrochloric Acid SCHEMBL31460385 | 0.76 | MEN1 (0.42) | MAPTTDP1GRM5PRSS1ACR | |
| SCHEMBL28577779 | 0.76 | EGFR (0.49) | GRM5EGFRPTGS2 | |
| SCHEMBL29187684 | 0.75 | ELANE (0.49) | MAPTGRM5MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1140450-A | Potassium salts of biphenylmethane derivatives and medicaments containing them | WAKUNAGA SEIYAKU KK (JP) | 1997-01-15 | — | — | CN | disclosed |