Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468216 | 0.80 | CYP11B1 (0.44) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL4546575 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPK1ATMLMNASMN1; SMN2 | |
| SCHEMBL3293810 | 0.74 | EPHX2 (0.47) | ALDH1A1ATMLMNASMN1; SMN2KMT2A | |
| SCHEMBL6541587 | 0.73 | KMT2A (0.51) | ALDH1A1MAPK1ATMLMNAKMT2A | |
| SCHEMBL2076261 | 0.70 | CRBN (0.42) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL6541451 | 0.70 | ALDH1A1 (0.36) | ALDH1A1MAPK1ATMLMNASMN1; SMN2 | |
| SCHEMBL27498007 | 0.67 | KMT2A (0.39) | ALDH1A1MAPK1ATMLMNASMN1; SMN2 | |
| SCHEMBL378251 | 0.66 | TOP2A (0.50) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL6541572 | 0.66 | PGR (0.53) | CYP11B1CYP11B2 | |
| SCHEMBL6541666 | 0.65 | PGR (0.58) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201820-C | Compositions containing benzimidazolones and progestogens | WYETH CORP (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1152020-C | Benzimidazolrone and analogues, and the use as ligand of progesterone | �Ʒ� | 2004-06-02 | — | — | CN | disclosed |
| CN-1349511-A | Benzimidazolrone and analogues, and the use as ligand of progesterone | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1349411-A | Compositions containing benzimidazolones and progestogens | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |