Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597500 | 0.85 | TOP2A (0.50) | TOP2ATOP2BMAPTTDP1ALDH1A1 | |
| SCHEMBL10765254 | 0.81 | TOP2A (0.46) | TOP2ATOP2BMAPTTDP1ALDH1A1 | |
| SCHEMBL27618934 | 0.81 | TOP2A (0.46) | TOP2ATOP2BMAPTTDP1ALDH1A1 | |
| SCHEMBL11086765 | 0.81 | TOP2A (0.46) | TOP2ATOP2BMAPTTDP1ALDH1A1 | |
| SCHEMBL13737400 | 0.79 | TOP2A (0.45) | TOP2ATOP2BMAPTTDP1ALDH1A1 | |
| SCHEMBL25495305 | 0.79 | TOP2A (0.45) | TOP2ATOP2BMAPTTDP1ALDH1A1 | |
| SCHEMBL18589477 | 0.79 | TOP2A (0.45) | TOP2ATOP2BMAPTTDP1ALDH1A1 | |
| SCHEMBL11612516 | 0.79 | TOP2A (0.34) | TOP2ATOP2BMAPTTDP1ALDH1A1 | |
| SCHEMBL5592306 | 0.78 | TOP2A (0.48) | TOP2ATOP2BMAPTTDP1ALDH1A1 | |
| SCHEMBL6534633 | 0.78 | TOP2A (0.44) | TOP2ATOP2BMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448414-B1 | STABILIZED AND ACTIVATED BROMINE SOLUTIONS AS A BIOCIDE AND AS AN ANTIFOULING AGENT | BROMINE COMPOUNDS LTD (IL) | 2019-04-24 | — | — | EP | claimed |
| EP-1556547-B1 | ADDITIVE AND METHOD FOR AVOIDING OR AT LEAST REDUCING DEPOSITS IN WATER BEARING AND/OR CONTACTING INDUSTRIAL SYSTEMS | POHLEN ALFRED (LU) | 2010-05-12 | — | — | EP | claimed |
| EP-2165981-A1 | Antimicrobial water treatment | LONZA, INC. (US) | 2010-03-24 | — | — | EP | claimed |
| US-RE39021-E1 | Hydantoin-enhanced halogen efficacy in pulp and paper applications | LONZA INC. (US) | 2006-03-21 | — | — | US | claimed |
| EP-0785909-B1 | HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS | LONZA AG (US) | 2003-04-16 | — | — | EP | claimed |
| US-20030039580-A1 | Stable preservative formulations comprising halopropynyl compounds and butoxydiglycol solvent | LONZA INC. (US) | 2003-02-27 | — | — | US | claimed |
| JP-2002544144-A | — | — | 2002-12-24 | — | — | JP | claimed |
| WO-2002067685-A1 | STABLE PRESERVATIVE FORMULATIONS COMPRISING HALOPROPYNYL COMPOUNDS AND BUTOXYDIGLYCOL SOLVENT | LONZA INC. (US) | 2002-09-06 | — | — | WO | claimed |
| EP-1071330-B1 | STABILIZATION OF ISOTHIAZOLONE | LONZA AG (US) | 2002-08-21 | — | — | EP | claimed |
| EP-1071330-A1 | STABILIZATION OF ISOTHIAZOLONE | LONZA INC. (US) | 2001-01-31 | — | — | EP | claimed |
| EP-0859692-A4 | HALOHYDANTOIN FORMS AND METHOD BY MELT EXTRUSION | LONZA AG (US) | 1999-02-03 | — | — | EP | claimed |
| EP-0859692-A1 | HALOHYDANTOIN FORMS AND METHOD BY MELT EXTRUSION | LONZA INC. (US) | 1998-08-26 | — | — | EP | claimed |
| US-5750061-A | EXTRUDING WITH PARTIAL MELTING FOR DUSTLESS SOLID PRODUCT | LONZA INC. (US) | 1998-05-12 | — | — | US | claimed |
| EP-0785909-A4 | HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS | LONZA AG (US) | 1998-02-25 | — | — | EP | claimed |
| EP-0785909-A1 | HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS | LONZA, INC. (US) | 1997-07-30 | — | — | EP | claimed |
| WO-1997017180-A1 | HALOHYDANTOIN FORMS AND METHOD BY MELT EXTRUSION | LONZA INC. (US) | 1997-05-15 | — | — | WO | claimed |
| US-5565109-A | SLIMICIDES | LONZA INC. (US) | 1996-10-15 | — | — | US | claimed |
| WO-1996011882-A1 | HYDANTOIN-ENHANCED HALOGEN EFFICACY IN PULP AND PAPER APPLICATIONS | LONZA INC. (US) | 1996-04-25 | — | — | WO | claimed |
| US-4560766-A | Shaped halogenated hydantoins | GLYCO CHEMICALS, INC. (US) | 1985-12-24 | — | — | US | claimed |
| US-4537697-A | Method of enhancing solubility of halogenated hydantoins | GLYCO, INC. (US) | 1985-08-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030039580-A1 | Stable preservative formulations comprising halopropynyl compounds and butoxydiglycol solvent | DDC, HDHD5, GMDS | TOP2A 3774/4885TOP2B 3594/4885MAPT 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.