Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345266 | 0.87 | KDM4E (0.62) | KDM4ELMNAGABRR1HTR2CGLRA1 | |
| SCHEMBL27804583 | 0.87 | KDM4E (0.62) | KDM4ELMNAGABRR1HTR2CGLRA1 | |
| SCHEMBL5664524 | 0.83 | KDM4E (0.58) | KDM4ELMNAGABRR1HTR2CGLRA1 | |
| SCHEMBL3622179 | 0.82 | ALDH1A1 (0.45) | LMNAALDH1A1TSHRKDM6BKDM5C | |
| SCHEMBL28419062 | 0.79 | KDM4E (0.59) | KDM4ELMNAGABRR1HTR2CALDH1A1 | |
| SCHEMBL3335940 | 0.78 | ALDH1A1 (0.46) | KDM4ELMNAHTR2CALDH1A1TSHR | |
| SCHEMBL28498302 | 0.77 | KDM4E (0.52) | KDM4ELMNAGABRR1HTR2CALDH1A1 | |
| SCHEMBL27696082 | 0.77 | — | — | |
| SCHEMBL115119 | 0.76 | — | — | |
| SCHEMBL28900079 | 0.76 | KDM4E (0.50) | KDM4ELMNAGABRR1HTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178521-A | Esters of 5-aminolevulinic acid as photosensitizers in photochemotherapy | NORWEGIAN RADIUM HOSPITAL RESE (NO) | 1998-04-08 | — | — | CN | claimed |
| CN-1137087-C | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy | �Ƹ��� | 2004-02-04 | — | — | CN | disclosed |
| CN-1178521-A | Esters of 5-aminolevulinic acid as photosensitizers in photochemotherapy | NORWEGIAN RADIUM HOSPITAL RESE (NO) | 1998-04-08 | — | — | CN | disclosed |