Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804583 | 0.91 | KDM4E (0.62) | KDM4ELMNAHTR2CALDH1A1GABRR1 | |
| SCHEMBL15345266 | 0.91 | KDM4E (0.62) | KDM4ELMNAHTR2CALDH1A1GABRR1 | |
| SCHEMBL5664524 | 0.86 | KDM4E (0.58) | KDM4ELMNAHTR2CALDH1A1GABRR1 | |
| SCHEMBL28433422 | 0.85 | HTR2C (0.61) | KDM4ELMNAHTR2CALDH1A1GABRR1 | |
| SCHEMBL27624661 | 0.83 | ALDH1A1 (0.55) | KDM4ELMNAHTR2CALDH1A1TSHR | |
| SCHEMBL21518705 | 0.83 | ALDH1A1 (0.67) | ALDH1A1TSHRCYP1A2TDP1NAAA | |
| SCHEMBL28498302 | 0.80 | KDM4E (0.52) | KDM4ELMNAHTR2CALDH1A1GABRR1 | |
| SCHEMBL27468792 | 0.79 | KDM4E (0.56) | KDM4ELMNAHTR2CALDH1A1GABRR1 | |
| SCHEMBL28207529 | 0.78 | ALDH1A1 (0.55) | KDM4ELMNAHTR2CALDH1A1GABRR1 | |
| Hydrochloric Acid SCHEMBL12611638 | 0.78 | HTR2C (0.61) | KDM4ELMNAHTR2CALDH1A1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113980883-A | Recombinant escherichia coli for high-yield hydroxylated steroid bulk drug and application thereof | 浙江理工大学 | 2022-01-28 | — | — | CN | claimed |
| CN-113980883-A | Recombinant escherichia coli for high-yield hydroxylated steroid bulk drug and application thereof | 浙江理工大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-111356760-A | Lyophilized compositions and methods of bacteria or listeria strains | 阿德瓦希斯公司 | 2020-06-30 | — | — | CN | disclosed |