SCHEMBL2746920

SCHEMBL2746920

C#Cc1c(Oc2ccc(N)c(O)c2)cccc1Oc1ccc(N)c(O)c1.c1cc2ccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP3A4 P08684 1/20 0.41
GAA P10253 5/20 0.36
RCE1 Q9Y256 1/20 0.36
F10 P00742 1/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 4/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
TSHR P16473 1/20 0.34
MMP2 P08253 1/20 0.34
MMP14 P50281 1/20 0.34
PTPN22 Q9Y2R2 1/20 0.34
NR4A1 P22736 1/20 0.33
IKBKB O14920 1/20 0.33
BRAF P15056 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL716943 0.78 GAA (0.52) ALOX15HSD17B10CYP3A4GAARCE1
SCHEMBL2748471 0.77 ALOX15 (0.38) ALOX15HSD17B10CYP3A4GAARCE1
SCHEMBL4849002 0.77 GAA (0.47) ALOX15HSD17B10CYP3A4GAARCE1
SCHEMBL1348470 0.76 CYP3A4 (0.58) ALOX15HSD17B10CYP3A4GAAALDH1A1
SCHEMBL2747603 0.75 NR4A1 (0.40) ALOX15HSD17B10CYP3A4GAARCE1
SCHEMBL2749941 0.75 NR4A1 (0.40) ALOX15HSD17B10CYP3A4GAARCE1
SCHEMBL11224092 0.74 GAA (0.45) CYP3A4GAARCE1F10ALDH1A1
SCHEMBL6856538 0.74 NCOA1 (0.55) ALOX15HSD17B10CYP3A4GAARCE1
Biphenyl SCHEMBL3476095 0.73 MEN1 (0.52) ALOX15HSD17B10CYP3A4GAAALDH1A1
SCHEMBL2747299 0.73 GAA (0.35) ALOX15HSD17B10CYP3A4GAARCE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed