SCHEMBL2747299

SCHEMBL2747299

C#Cc1ccc2c(Oc3ccc(N)c(O)c3)cccc2c1Oc1ccc(N)c(O)c1.c1cc2cc-2c1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
RCE1 Q9Y256 1/20 0.35
TLR4 O00206 1/20 0.32
ESR1 P03372 2/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
F10 P00742 1/20 0.32
ALDH1A1 P00352 1/20 0.31
AR P10275 1/20 0.31
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2748123 0.86 ESR1 (0.36) GAAESR1CYP3A4ALOX15HSD17B10
SCHEMBL2747148 0.80 GAA (0.37) GAARCE1TLR4CYP3A4HSD17B10
SCHEMBL2748471 0.80 ALOX15 (0.38) GAARCE1ESR1CYP3A4ALOX15
SCHEMBL4849002 0.79 GAA (0.47) GAARCE1TLR4CYP3A4ALOX15
SCHEMBL2746863 0.74 GAA (0.30) GAARCE1
SCHEMBL2747389 0.74 GAA (0.30) GAARCE1
SCHEMBL2749941 0.74 NR4A1 (0.40) GAARCE1ESR1CYP3A4ALOX15
SCHEMBL2746920 0.73 ALOX15 (0.41) GAARCE1TLR4CYP3A4ALOX15
SCHEMBL2747068 0.72 ESR1 (0.37) GAAESR1THRATHRB
SCHEMBL2747567 0.72 ESR1 (0.41) GAARCE1ESR1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed