SCHEMBL716943

SCHEMBL716943

Nc1ccc(Oc2ccccc2Oc2ccc(N)c(O)c2)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.52
RCE1 Q9Y256 1/20 0.52
ALOX15 P16050 2/20 0.45
CYP3A4 P08684 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NR4A1 P22736 1/20 0.45
ALDH1A1 P00352 2/20 0.44
F10 P00742 1/20 0.43
TSHR P16473 2/20 0.43
HTT P42858 3/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TLR4 O00206 1/20 0.41
MMP2 P08253 1/20 0.41
MMP14 P50281 1/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 1/20 0.41
MEN1 O00255 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4841637 0.89 GAA (0.53) GAARCE1ALOX15CYP3A4HSD17B10
SCHEMBL11224092 0.88 GAA (0.45) GAARCE1CYP3A4ALDH1A1F10
SCHEMBL4849002 0.87 GAA (0.47) GAARCE1ALOX15CYP3A4HSD17B10
SCHEMBL30040301 0.85 NR4A1 (0.61) GAAALOX15CYP3A4HSD17B10NR4A1
SCHEMBL436522 0.85 NR4A1 (0.61) GAAALOX15CYP3A4HSD17B10NR4A1
SCHEMBL28336683 0.85 NCOA1 (0.61) GAARCE1ALOX15CYP3A4HSD17B10
SCHEMBL30233344 0.84 LTA4H (0.59) GAAALOX15CYP3A4HSD17B10NR4A1
SCHEMBL720127 0.84 ALDH1A1 (0.55) GAARCE1ALOX15HSD17B10NR4A1
SCHEMBL564952 0.84 LTA4H (0.59) GAAALOX15CYP3A4HSD17B10NR4A1
SCHEMBL6856538 0.84 NCOA1 (0.55) GAARCE1ALOX15CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9123689-B2 Epoxy resin composition, method for producing same, and semiconductor device using same TORAY INDUSTRIES, INC. (JP) 2015-09-01 US disclosed
US-20140005318-A1 EPOXY RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND SEMICONDUCTOR DEVICE USING SAME TORAY INDUSTRIES, INC. (JP) 2014-01-02 US disclosed
US-8216727-B2 Aromatic hydrocarbon based proton exchange membrane and direct methanol fuel cell using same TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-07-10 US disclosed
US-20120052411-A9 AROMATIC HYDROCARBON BASED PROTON EXCHANGE MEMBRANE AND DIRECT METHANOL FUEL CELL USING SAME TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-03-01 US disclosed
US-7799893-B2 Polybenzazole block copolymer SOLVAY (SOCIETE ANONYME) (BE) 2010-09-21 US disclosed
EP-1812497-B1 POLYBENZAZOLE BLOCK COPOLYMER SOLVAY (BE) 2009-06-17 EP disclosed
US-7365231-B2 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2008-04-29 US disclosed
US-20080003480-A1 recurring units comprising at least one benzazole group chosen among benzoxazole group and benzothiazole group; solid polymer electrolyte membrane, fuel cell SOLVAY (SOCIETE ANONYME) (BE) 2008-01-03 US disclosed
US-7288603-B2 Polybenzazole compound having sulfonic acid group and/or phosphonic acid group, resin composition containing the same, resin molding, solid polymer electrolyte membrane, solid polymer electrolyte membrane/electrode assembly and method of preparing assembly TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-10-30 US disclosed
US-20070207361-A1 AROMATIC HYDROCARBON BASED PROTON EXCHANGE MEMBRANE AND DIRECT METHANOL FUEL CELL USING SAME TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-09-06 US disclosed
EP-1812497-A1 POLYBENZAZOLE BLOCK COPOLYMER Solvay SA (BE) 2007-08-01 EP disclosed
US-20060241187-A1 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2006-10-26 US disclosed
WO-2006053808-A1 COLOUR-RECOGNITION DEVICE MAURER DAVID (CH) 2006-05-26 WO disclosed
WO-2006051064-A1 POLYBENZAZOLE BLOCK COPOLYMER Solvay (Société Anonyme) (BE) 2006-05-18 WO disclosed
EP-1657274-A1 Polybenzazole block copolymer SOLVAY (Société Anonyme) (BE) 2006-05-17 EP disclosed
EP-1354907-B1 POLYBENZAZOLE COMPOUND HAVING SULFO GROUP AND/OR PHOSPHONO GROUP, RESIN COMPOSITION CONTAINING THE SAME, MOLDED RESIN, SOLID POLYMER ELECTROLYTE FILM, SOLID ELECTROLYTE FILM/ELECTRODE CATALYST LAYER COMPOSITE, AND PROCESS FOR PRODUCING THE COMPOSITE TOYO BOSEKI (JP) 2006-03-01 EP disclosed
US-20040062969-A1 Polybenzazole compound having sulfo group and/or phosphono group, resin composition containing the same, molded resin, slid polymer electrolyte film, solid electrolyte film/electrode catalyst layer composite, and process for producing the composite TOYO BOSEKI KABUSHIKI KAISHA (JP) 2004-04-01 US disclosed
CN-1474844-A Polybenzole compound having sulfo group and/or phosphono group, resin composition containing same, molded resin, solid polymer electrotyte film, solid electrolyte film/electrode catalyst layer ... �����֯��ʽ���� 2004-02-11 CN disclosed
EP-1354907-A1 POLYBENZAZOLE COMPOUND HAVING SULFO GROUP AND/OR PHOSPHONO GROUP, RESIN COMPOSITION CONTAINING THE SAME, MOLDED RESIN, SOLID POLYMER ELECTROLYTE FILM, SOLID ELECTROLYTE FILM/ELECTRODE CATALYST LAYER COMPOSITE, AND PROCESS FOR PRODUCING THE COMPOSITE Toyo Boseki Kabushiki Kaisha (JP) 2003-10-22 EP disclosed
US-5288588-A Containing diamine substituted with phenolic hydroxyl, carboxyl, thiophenol and/or sulfonic groups NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241187-A1 Compound with antitumor activity and preparation method therefor WEE1, WEE2, CYP51A1 GAA 682/4885RCE1 212/4885ALOX15 491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.