Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11708960 | 0.81 | TYR (0.45) | CYP3A4HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL2789834 | 0.78 | ALDH1A1 (0.54) | CYP3A4HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL11210466 | 0.76 | CYP3A4 (0.43) | CYP3A4HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL21302111 | 0.75 | HSD17B10 (0.46) | CYP3A4HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL8392107 | 0.75 | CYP3A4 (0.46) | CYP3A4HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL10662295 | 0.70 | HSD17B10 (0.50) | CYP3A4HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL11317922 | 0.70 | HSD17B10 (0.50) | CYP3A4HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL11379540 | 0.69 | MEN1 (0.48) | CYP3A4HSD17B10ALDH1A1TSHRTDP1 | |
| SCHEMBL25039097 | 0.68 | MEN1 (0.41) | CYP3A4HSD17B10ALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL30553151 | 0.68 | ALOX15 (0.44) | CYP3A4HSD17B10ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1076449-A | Imidazopyridine derivatives and medicament | JAPAN NEW MEDICINALLY CO LTD | 1993-09-22 | — | — | CN | disclosed |