Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046238 | 0.74 | ALDH1A1 (0.47) | MAPK1MAPTALDH1A1MEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL28040925 | 0.74 | TDP1 (0.39) | MAPK1MAPTALDH1A1GAAKDM4E | |
| Ethoxycarbonyl Group SCHEMBL28040931 | 0.74 | TDP1 (0.39) | MAPK1MAPTALDH1A1GAAKDM4E | |
| SCHEMBL1467189 | 0.72 | MAPK1 (0.63) | MAPK1MAPTALDH1A1MEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL28127282 | 0.71 | PIK3CA (0.47) | MAPK1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9380208 | 0.70 | LMNA (0.50) | MAPK1MAPTALDH1A1KDM4EPKM | |
| Ethoxycarbonyl Group SCHEMBL27884569 | 0.70 | UHRF1 (0.37) | ALDH1A1MEN1KMT2AKDM4EPKM | |
| SCHEMBL19957497 | 0.68 | CYP3A4 (0.39) | ALDH1A1ATMKDM4ENMT1CYP3A4 | |
| SCHEMBL13826922 | 0.67 | AXL (0.42) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22314743 | 0.67 | LMNA (0.43) | MAPK1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168667-A | Pyridopyrimidones, quinolines and fused N-heretocycles as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-12-24 | — | — | CN | disclosed |