Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | F13A1 | P00488 | 1/20 | 0.30 |
| ▸ | TGM1 | P22735 | 1/20 | 0.30 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.30 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL27873789 | 0.95 | TSHR (0.42) | TGM2TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL4354008 | 0.89 | TSHR (0.50) | TGM2TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL15004 | 0.89 | — | — | |
| SCHEMBL27471616 | 0.88 | ZDHHC20 (0.44) | TGM2TSHRALDH1A1MAPK1TDP1 | |
| Sulfuric Acid SCHEMBL16268484 | 0.88 | ZDHHC20 (0.44) | TGM2TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL1292666 | 0.86 | TSHR (0.37) | TGM2TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL28523135 | 0.86 | TSHR (0.46) | TGM2TSHRALDH1A1MAPK1TDP1 | |
| Methyl Alcohol SCHEMBL28509086 | 0.86 | — | — | |
| Methyl Alcohol SCHEMBL28641407 | 0.86 | TSHR (0.48) | TGM2TSHRALDH1A1MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL4773602 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104737018-B | Part graft base | 3M创新有限公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-103119074-B | Monomer composition containing unsaturated polyalkylene glycol ether-based monomer, method for producing composition, polymer obtained using composition, and method for producing polymer | NIPPON CATALYTIC CHEM IND | 2015-04-15 | — | — | CN | disclosed |
| CN-101910268-B | Porous polymeric resins | 3M INNOVATIVE PROPERTIES CO | 2014-07-30 | — | — | CN | disclosed |
| CN-102336845-B | Method for synthesizing polycarboxylic acid water reducer | SHANGHAI TAIJIE CHEMICAL CO LTD | 2014-04-30 | — | — | CN | disclosed |
| CN-102112412-B | Shrinkage-reducing agent for hydraulic material and shrinkage-reducing agent composition for hydraulic material | NIPPON CATALYTIC CHEM IND | 2013-12-18 | — | — | CN | disclosed |
| CN-103119074-A | Monomer composition containing unsaturated polyalkylene glycol ether-based monomer, method for producing composition, polymer obtained using composition, and method for producing polymer | NIPPON CATALYTIC CHEM IND | 2013-05-22 | — | — | CN | disclosed |
| CN-102149747-A | Multibranched polyalkylene glycol polymer and manufacturing method thereof, and cement admixture | NIPPON CATALYTIC CHEM IND | 2011-08-10 | — | — | CN | disclosed |
| CN-102112412-A | Shrinkage-reducing agent for hydraulic material and shrinkage-reducing agent composition for hydraulic material | NIPPON CATALYTIC CHEM IND | 2011-06-29 | — | — | CN | disclosed |
| CN-101353399-B | Polycarboxylic acid type copolymer and cement additive containing polycarboxylic acid type copolymer | NIPPON CATALYTIC CHEM IND | 2010-12-15 | — | — | CN | disclosed |
| CN-101910268-A | Porous polymeric resins | 3M INNOVATIVE PROPERTIES CO | 2010-12-08 | — | — | CN | disclosed |
| CN-1863946-A | Protein crystallization device, protein crystallization method, protein crystallization agent and preparation method thereof | MITSUBISHI RAYON CO (JP) | 2006-11-15 | — | — | CN | disclosed |
| CN-1284742-C | Cement dispersant, method for producing same, and cement composition using same | NIPPON CATALYTIC CHEM IND (JP) | 2006-11-15 | — | — | CN | disclosed |
| CN-1807476-A | Polycarboxylic acid copolymer, production method and use thereof | NIPPON CATALYTIC CHEM IND (JP) | 2006-07-26 | — | — | CN | disclosed |
| CN-1243777-C | Polycarboxylic acid type copolymer, and preparation method and use thereof | NIPPON CATALYTIC CHEM IND (JP) | 2006-03-01 | — | — | CN | disclosed |
| CN-1673240-A | N-vinyl amide polymer and production method thereof | NIPPON CATALYTIC CHEM IND (JP) | 2005-09-28 | — | — | CN | disclosed |
| CN-1618941-A | Detergent builder and detergent composition | NIPPON CATALYTIC CHEM IND (JP) | 2005-05-25 | — | — | CN | disclosed |
| CN-1537126-A | Polycarboxylic acid type copolymer, and preparation method and use thereof | 株式会社日本触媒 | 2004-10-13 | — | — | CN | disclosed |
| CN-1148329-C | Cement dispersant agent and cement compsn. using same | 株式会社日本触媒 | 2004-05-05 | — | — | CN | disclosed |
| CN-1412145-A | Cement dispersant, method for producing same, and cement composition using same | NIPPON CATALYTIC CHEM IND (JP) | 2003-04-23 | — | — | CN | disclosed |
| CN-1343642-A | Cement dispersant agent and cement compsn. using same | NIPPON CATALYTIC CHEM IND (JP) | 2002-04-10 | — | — | CN | disclosed |