Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18205166 | 0.81 | CYP2C9 (0.45) | CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL27256861 | 0.80 | CYP1A2 (0.44) | CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL21028193 | 0.79 | CYP1A2 (0.44) | CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL17287129 | 0.79 | MMP1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13866419 | 0.78 | MMP1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL12460865 | 0.77 | RAB9A (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL27269464 | 0.76 | CYP1A2 (0.42) | CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL27269524 | 0.76 | CYP1A2 (0.42) | CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL18212467 | 0.75 | CYP1A2 (0.43) | CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL27469778 | 0.75 | CYP1A2 (0.43) | CYP2C9CYP1A2CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |