Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
| ▸ | RXRG | P48443 | 1/20 | 0.52 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22445719 | 0.81 | LDHA (0.57) | LDHARXRAP4HA1P4HTMHDAC1 | |
| SCHEMBL8521764 | 0.80 | P4HTM (0.73) | LDHAP4HA1P4HTMALDH1A1 | |
| SCHEMBL13876205 | 0.80 | EPHX2 (0.66) | RORCHSD17B13HDAC3HDAC1HDAC2 | |
| SCHEMBL21310804 | 0.80 | KDM4C (0.56) | RXRARXRBRXRGP4HA1CSNK2A2 | |
| SCHEMBL8303037 | 0.78 | LDHA (0.57) | LDHARXRARXRBRXRGP4HA1 | |
| SCHEMBL536004 | 0.78 | FFAR4 (0.59) | RXRARXRBRXRGCSNK2A2CSNK2B | |
| SCHEMBL16195648 | 0.77 | SCN9A (0.48) | CSNK2A2CSNK2BFFAR4ABL1SCN9A | |
| SCHEMBL14089991 | 0.77 | RXRA (0.54) | RXRARXRBRXRGCSNK2A2CSNK2B | |
| SCHEMBL14744175 | 0.77 | ALOX5AP (0.51) | RORCFFAR4ABL1SCN10ASCN9A | |
| SCHEMBL4901543 | 0.76 | RXRA (0.51) | RXRARXRBRXRGCSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618978-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |