Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.51 |
| ▸ | FEN1 | P39748 | 3/20 | 0.51 |
| ▸ | MPL | P40238 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988502 | 0.79 | HSP90AA1 (0.50) | ALOX5APFEN1METAP2 | |
| SCHEMBL29739505 | 0.79 | HSP90AA1 (0.50) | ALOX5APFEN1METAP2 | |
| SCHEMBL266175 | 0.78 | RORC (0.54) | ALOX5APFEN1RORCCNR2SCN9A | |
| SCHEMBL8230055 | 0.77 | GRM5 (0.52) | ALOX5APFEN1MPLCNR2SCN9A | |
| SCHEMBL14244577 | 0.77 | ALOX5AP (0.56) | ALOX5APFEN1MPLSCN9AABL1 | |
| SCHEMBL27470293 | 0.77 | LDHA (0.53) | ALOX5APFEN1RORCSCN9AABL1 | |
| SCHEMBL3457107 | 0.76 | NCOA1 (0.54) | ALOX5APFEN1MEN1KMT2AFFAR4 | |
| SCHEMBL14744389 | 0.76 | RORC (0.45) | ALOX5APFEN1RORCCNR2SCN9A | |
| SCHEMBL2406803 | 0.76 | ALOX5AP (0.48) | ALOX5APFEN1MPLCNR2HSD11B1 | |
| SCHEMBL14726481 | 0.75 | MPL (0.76) | MPLSCN9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |