Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947037 | 0.79 | PLA2G2A (0.49) | PLA2G2ALMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL7955788 | 0.74 | LMNA (0.44) | PPARGNR1H4LMNAL3MBTL1MAPT | |
| SCHEMBL7947040 | 0.73 | CNR1 (0.46) | PLA2G2ANR1H4L3MBTL1ALDH1A1 | |
| SCHEMBL8890454 | 0.73 | FFAR1 (0.59) | LTA4HALOX5NR1H4LMNAL3MBTL1 | |
| SCHEMBL7881965 | 0.72 | SRD5A2 (0.47) | PPARGLMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL27474224 | 0.72 | CNR1 (0.45) | PLA2G2ANR1H4L3MBTL1ALDH1A1 | |
| SCHEMBL8887581 | 0.72 | FFAR1 (0.58) | LTA4HALOX5NR1H4LMNAL3MBTL1 | |
| SCHEMBL8888760 | 0.72 | FFAR1 (0.58) | LTA4HALOX5NR1H4LMNAL3MBTL1 | |
| SCHEMBL8890073 | 0.72 | FFAR1 (0.58) | LTA4HALOX5NR1H4LMNAL3MBTL1 | |
| SCHEMBL1115103 | 0.70 | LTA4H (0.65) | LTA4HNR1H4LMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161334-A | Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof | SUMITOMO PHARMA (JP) | 1997-10-08 | — | — | CN | disclosed |