Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394938 | 0.88 | ALDH1A1 (0.56) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL26978217 | 0.86 | ALDH1A1 (0.51) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL468298 | 0.85 | LMNA (0.52) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7893567 | 0.84 | MEN1 (0.67) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7888701 | 0.84 | ALDH1A1 (0.52) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL4417928 | 0.81 | ALDH1A1 (0.47) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7890296 | 0.80 | LMNA (0.50) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL12488387 | 0.79 | ALDH1A1 (0.52) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7585320 | 0.79 | ALDH1A1 (0.52) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL2120954 | 0.78 | CYP2D6 (0.46) | LMNANPSR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522616-A | Indole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2009-09-02 | — | — | CN | claimed |
| CN-1181050-C | Novel substituted dimeric compounds, its preparing process and medicinal compsns. containing same | ɪά��ʵ���� | 2004-12-22 | — | — | CN | claimed |
| CN-1273967-A | Novel substituted dimeric compounds, its preparing process and medicinal compsns. containing same | ADIR (FR) | 2000-11-22 | — | — | CN | claimed |
| CN-101522616-A | Indole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2009-09-02 | — | — | CN | disclosed |
| CN-1181050-C | Novel substituted dimeric compounds, its preparing process and medicinal compsns. containing same | ɪά��ʵ���� | 2004-12-22 | — | — | CN | disclosed |
| CN-1128142-C | Novel substituted dipolymer compounds, prepn. method therefor, pharmaceutical compositions contg. same | ADIR (FR) | 2003-11-19 | — | — | CN | disclosed |
| CN-1277962-A | Novel substituted dipolymer compounds, prepn. method therefor, pharmaceutical compositions contg. same | ADIR (FR) | 2000-12-27 | — | — | CN | disclosed |
| CN-1273967-A | Novel substituted dimeric compounds, its preparing process and medicinal compsns. containing same | ADIR (FR) | 2000-11-22 | — | — | CN | disclosed |