Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27474102 | 0.80 | LMNA (0.58) | LMNANPSR1NR4A2GPR84ALDH1A1 | |
| SCHEMBL27880558 | 0.76 | F7 (0.51) | LMNANPSR1NR4A2GPR84F7 | |
| SCHEMBL7895153 | 0.75 | CSNK2A2 (0.50) | LMNANPSR1NR4A2SLC6A4ALDH1A1 | |
| SCHEMBL14631648 | 0.74 | NR4A2 (0.44) | LMNANPSR1NR4A2GPR84F7 | |
| SCHEMBL24812458 | 0.71 | MEN1 (0.55) | LMNANR4A2GPR84SLC6A4ALDH1A1 | |
| SCHEMBL3182218 | 0.71 | NR4A2 (0.69) | NR4A2GPR84F7F3ALDH1A1 | |
| SCHEMBL13533538 | 0.71 | NR4A2 (0.64) | LMNANPSR1NR4A2GPR84F7 | |
| SCHEMBL24815224 | 0.71 | GPR84 (0.63) | LMNANR4A2GPR84F7F3 | |
| SCHEMBL30392504 | 0.71 | F7 (0.74) | LMNANR4A2GPR84F7F3 | |
| SCHEMBL613332 | 0.71 | F7 (0.74) | LMNANR4A2GPR84F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180657-B1 | SLEEP DISORDERS | ELI LILLY AND COMPANY | 2001-01-30 | — | — | US | disclosed |