Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747368 | 0.89 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL28061456 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL28289200 | 0.81 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL29398766 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL8717 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL28542371 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL18311802 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL31106427 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL28751085 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL28014365 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178077-B2 | Drug development target protein and target gene, and method of screening | REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20090233274-A1 | DRUG DEVELOPMENT TARGET PROTEIN AND TARGET GENE, AND METHOD OF SCREENING | REVERSE PROTEOMICS RESEARCH INSTITUTE CO. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-3981887-A | Sulfoxides and sulfones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233274-A1 | DRUG DEVELOPMENT TARGET PROTEIN AND TARGET GENE, AND METHOD OF SCREENING | NCS1, PRSS12, TPX2 | ALDH1A1 4286/4885HPGD 3875/4885KDM4E 4343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.