SCHEMBL27474261

SCHEMBL27474261

CN(N)C(=O)OC1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.44
NAAA Q02083 2/20 0.41
HTT P42858 1/20 0.40
CYP2C19 P33261 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
CYP19A1 P11511 2/20 0.36
FABP7 O15540 1/20 0.36
FABP5 Q01469 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP12 P39900 1/20 0.36
STS P08842 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15565387 0.94 EPHX1 (0.37) EPHX1NAAAHTTCYP2C19CA12
SCHEMBL5622283 0.83 EPHX1 (0.47) EPHX1NAAAHTTCYP2C19CA12
SCHEMBL11776636 0.81 EPHX1 (0.46) EPHX1NAAAHTTCYP2C19CA12
SCHEMBL14759201 0.80 EPHX1 (0.44) EPHX1NAAAHTTCYP2C19CA12
SCHEMBL2220318 0.80 KAT2B (0.36)
Hydrochloric Acid SCHEMBL11683263 0.79 EPHX1 (0.44) EPHX1NAAAHTTCYP2C19CA12
SCHEMBL9863767 0.78 EPHX1 (0.41) EPHX1NAAAHTTCYP2C19CA12
SCHEMBL31562551 0.77 EPHX1 (0.41) EPHX1NAAAHTTCYP2C19CA12
Trimethylammonium SCHEMBL28173745 0.77 EPHX1 (0.46) EPHX1NAAAHTTCYP2C19CA12
SCHEMBL8493664 0.76 NAAA (0.42) EPHX1NAAAHTTCYP2C19CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103553972-B Method for the preparation of n-substituted carbamic acid ester and method for the preparation of isocyanate using the n-substituted carbamic acid ester 旭化成株式会社 2017-04-12 CN disclosed
CN-103588680-B N-substituted carbamate conveying with and storage compositions and manufacture isocyanates method 旭化成株式会社 2016-08-10 CN disclosed
CN-1171862-C Synthetic method for closed isocyanate containing alpha-olefinic bond 中国科学院长春应用化学研究所 2004-10-20 CN disclosed
CN-1326927-A Synthetic method for closed isocyanate containing alpha-olefinic bond CHANGCHUN APPLIED CHEMISTRY (CN) 2001-12-19 CN disclosed