SCHEMBL27474302

SCHEMBL27474302

NCc1ccccc1-c1[c]cccc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.50
PNMT P11086 3/20 0.39
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
CSNK2A3 Q8NEV1 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8010806 0.83 HSPA5 (0.34) DPP4
SCHEMBL6015094 0.80 PDCD1 (0.40) DPP4
SCHEMBL10500036 0.80 ALDH1A1 (0.33) DPP4
SCHEMBL982139 0.80 MGLL (0.37) DPP4CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL811836 0.80
SCHEMBL16862586 0.78 DPP4 (0.44) DPP4PNMTNOS3NOS1NOS2
SCHEMBL2761711 0.78 MEN1 (0.32)
SCHEMBL3452372 0.77
SCHEMBL11170779 0.77 HTR2A (0.40)
SCHEMBL983253 0.77 NR1H2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1159289-C C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cystenine proteases ������˹ҩƷ��˾ 2004-07-28 CN claimed
CN-104140441-A Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2014-11-12 CN disclosed
CN-104140448-A Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2014-11-12 CN disclosed
CN-104140445-A Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2014-11-12 CN disclosed
CN-104140442-A Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2014-11-12 CN disclosed
CN-101160345-B Method for producing aromatic polymer SUMITOMO CO LTD 2013-01-16 CN disclosed
CN-101611071-B Method for production of block copolymer SUMITOMO CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
CN-1628122-B Process for producing tertiary phosphine having bulky hydrocarbon group bonded HOKKO CHEM IND CO 2010-06-09 CN disclosed
CN-101611071-A The preparation method of segmented copolymer SUMITOMO CHEMICAL CO (JP) 2009-12-23 CN disclosed
CN-101595153-A Be used to prepare method that aromatic(based)polymer wherein is attached to the structure on the base material, contain the structure of the aromatic(based)polymer chain that is attached on the conductive base and contain the electron device of this structure SUMITOMO CHEMICAL CO (JP) 2009-12-02 CN disclosed
CN-101160345-A Method for producing aromatic polymer SUMITOMO CHEMICAL CO (JP) 2008-04-09 CN disclosed
CN-1628122-A Process for producing tertiary phosphine having bulky hydrocarbon group bonded HOKKO CHEM IND CO (JP) 2005-06-15 CN disclosed