Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982518 | 0.89 | NR1H2 (0.42) | NR1H2NR1H3PPARALIPG | |
| SCHEMBL981930 | 0.88 | NR1H2 (0.48) | NR1H2NR1H3PPARALIPG | |
| SCHEMBL17802343 | 0.86 | NR1H2 (0.50) | NR1H2NR1H3PPARALIPG | |
| SCHEMBL984057 | 0.86 | KDM4E (0.32) | NR1H2NR1H3 | |
| SCHEMBL983504 | 0.86 | NR1H2 (0.50) | NR1H2NR1H3PPARALIPG | |
| SCHEMBL982139 | 0.85 | MGLL (0.37) | NR1H2NR1H3 | |
| SCHEMBL3452372 | 0.81 | — | — | |
| SCHEMBL8010806 | 0.80 | HSPA5 (0.34) | — | |
| SCHEMBL7006299 | 0.78 | NPC1 (0.37) | NR1H2NR1H3PPARA | |
| SCHEMBL6704515 | 0.77 | PPARA (0.41) | NR1H2NR1H3PPARALIPGCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| EP-3606971-B1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL IP AMERICA INC (US) | 2022-01-12 | — | — | EP | disclosed |
| US-20200181359-A1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL IP AMERICA INC (US) | 2020-06-11 | — | — | US | disclosed |
| US-10597511-B2 | Reactive flame retardant blends for flexible polyurethane foam | ICL-IP AMERICA INC. (US) | 2020-03-24 | — | — | US | disclosed |
| EP-3606971-A1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL-IP America Inc. (US) | 2020-02-12 | — | — | EP | disclosed |
| WO-2019060035-A1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL-IP AMERICA INC. (US) | 2019-03-28 | — | — | WO | disclosed |
| US-20190085151-A1 | REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM | ICL-IP AMERICA INC. | 2019-03-21 | — | — | US | disclosed |
| EP-2275406-B1 | PROCESS FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-9233918-B2 | Isocyanate production process | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| WO-2015142613-A1 | PHOSPHATE ESTER-MODIFIED CLAY COMPOSITION, METHOD OF PRODUCING THE SAME AND FLAME-RETARDED PVC NANOCOMPOSITE, CONTAINING THE SAME | ICL-IP AMERICA INC. (US) | 2015-09-24 | — | — | WO | disclosed |
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-2275406-A1 | PROCESS FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| EP-0804507-A1 | SUBSTITUTED QUATERRYLENE TETRACARBOXYLIC ACID DIIMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022332-A1 | SUBSTITUTED QUATERRYLENE TETRACARBOXYLIC ACID DIIMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-25 | — | — | WO | disclosed |
| US-4895587-A | Haloacetamide compounds, process for production thereof, and use thereof as herbicide | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0206251-B1 | HALOACETAMIDE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1988-09-07 | — | — | EP | disclosed |
| EP-0206251-A1 | Haloacetamide compounds, process for production thereof, and use thereof as herbicide | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | CPS1, PHGDH, APEH | NR1H2 4195/4885NR1H3 4172/4885PPARA 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.