Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007179 | 0.97 | MAPT (0.44) | MAPTESR1ESR2LOXL2TAAR1 | |
| Fluoride SCHEMBL27920006 | 0.95 | MAPT (0.42) | MAPTESR1ESR2LOXL2TAAR1 | |
| Hydrochloric Acid SCHEMBL16880772 | 0.95 | MAPT (0.42) | MAPTESR1ESR2LOXL2TAAR1 | |
| SCHEMBL2012877 | 0.78 | MAPT (0.41) | MAPTESR1ESR2LOXL2TAAR1 | |
| SCHEMBL9339400 | 0.77 | ESR1 (0.39) | MAPTESR1ESR2LOXL2TAAR1 | |
| SCHEMBL9217667 | 0.76 | MAPT (0.47) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL3865502 | 0.75 | MGAM (0.40) | MAPTESR1ESR2LOXL2TAAR1 | |
| SCHEMBL9226507 | 0.74 | MAPT (0.45) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL2008775 | 0.73 | TAAR1 (0.39) | TAAR1HTR2ACYP2A6MAOBNOTUM | |
| SCHEMBL2006055 | 0.73 | LOXL2 (0.42) | MAPTLOXL2TAAR1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1174205-A | Carrier catalyst system, its prep, and use in polymerization of olefines thereof | HOECHST AG (DE) | 1998-02-25 | — | — | CN | disclosed |