Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16880772 | 0.97 | MAPT (0.42) | MAPTESR1ESR2LOXL2TAAR1 | |
| Fluoride SCHEMBL27920006 | 0.97 | MAPT (0.42) | MAPTESR1ESR2LOXL2TAAR1 | |
| SCHEMBL27474368 | 0.97 | MAPT (0.42) | MAPTESR1ESR2LOXL2TAAR1 | |
| SCHEMBL2012877 | 0.80 | MAPT (0.41) | MAPTESR1ESR2LOXL2TAAR1 | |
| SCHEMBL9339400 | 0.79 | ESR1 (0.39) | MAPTESR1ESR2LOXL2TAAR1 | |
| SCHEMBL9217667 | 0.78 | MAPT (0.47) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL3865502 | 0.77 | MGAM (0.40) | MAPTESR1ESR2LOXL2TAAR1 | |
| SCHEMBL9226507 | 0.76 | MAPT (0.45) | MAPTESR1ESR2NR1H2NR1H3 | |
| SCHEMBL2008775 | 0.75 | TAAR1 (0.39) | TAAR1HTR2ACYP2A6MAOBNOTUM | |
| SCHEMBL2006055 | 0.75 | LOXL2 (0.42) | MAPTLOXL2TAAR1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10053472-B2 | Silicon-based fungicides and process for producing the same | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-08-21 | — | — | US | claimed |
| EP-3089985-B1 | SILICON-BASED FUNGICIDES AND PROCESS FOR PRODUCING THE SAME | COUNCIL SCIENT IND RES (IN) | 2018-06-27 | — | — | EP | claimed |
| CN-106832376-A | Complex made of heterogeneous material and preparation method, electronic installation | 河源市美晨联合智能硬件电子研究院 | 2017-06-13 | — | — | CN | claimed |
| EP-2782920-B1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2016-12-21 | — | — | EP | claimed |
| US-20160326190-A1 | SILICON-BASED FUNGICIDES AND PROCESS FOR PRODUCING THE SAME | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-11-10 | — | — | US | claimed |
| EP-3089985-A1 | SILICON-BASED FUNGICIDES AND PROCESS FOR PRODUCING THE SAME | Council of Scientific and Industrial Research (IN) | 2016-11-09 | — | — | EP | claimed |
| WO-2015102025-A1 | SILICON-BASED FUNGICIDES AND PROCESS FOR PRODUCING THE SAME | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-07-09 | — | — | WO | claimed |
| US-20140315858-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | claimed |
| EP-2782920-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | claimed |
| CN-103958531-A | Fungicide N-[(trisubstitutedsilyl)methyl]-carboxamide derivatives | BAYER IP GMBH | 2014-07-30 | — | — | CN | claimed |
| WO-2013075817-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | claimed |
| US-7964738-B2 | Pharmaceutical compositions and methods of use of lipophilic, silicon-substituted, cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs and derivatives | SILAMED, INC. (US) | 2011-06-21 | — | — | US | claimed |
| US-20070129331-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | RND PHARMACEUTICALS, INC. (US) | 2007-06-07 | — | — | US | claimed |
| EP-1737471-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | RND Pharmaceuticals (US) | 2007-01-03 | — | — | EP | claimed |
| WO-2005102358-A2 | SILICONE-SUBSTITUTED COX-2 SELECTIVE INHIBITORS | RND PHARMACEUTICALS (US) | 2005-11-03 | — | — | WO | claimed |
| US-11129790-B2 | Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates | NORTHEASTERN UNIVERSITY (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200341395-A1 | TONER | CANON KABUSHIKI KAISHA (JP) | 2020-10-29 | — | — | US | disclosed |
| US-5089620-A | Monlinear optical effects | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 1992-02-18 | — | — | US | disclosed |
| US-5041589-A | Optics | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0404134-A1 | Organosilicon compounds and method for their preparation | Dow Corning Toray Silicone Company, Limited (JP) | 1990-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326190-A1 | SILICON-BASED FUNGICIDES AND PROCESS FOR PRODUCING THE SAME | CYP51A1, STS, LSS | MAPT 2179/4885ESR1 3165/4885ESR2 4200/4885 |
| US-10053472-B2 | Silicon-based fungicides and process for producing the same | CYP51A1, STS, LSS | MAPT 2179/4885ESR1 3165/4885ESR2 4200/4885 |
| US-20140315858-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | TET3, TET1, PFAS | MAPT 2807/4885ESR1 4377/4885ESR2 4494/4885 |
| US-11129790-B2 | Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates | GLUL, QPCT, DNPEP | MAPT 4290/4885ESR1 2812/4885ESR2 2734/4885 |
| US-20070129331-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | PTGES2, PTGS2, SI | MAPT 197/4885ESR1 253/4885ESR2 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.