Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412904 | 0.85 | MAPT (0.64) | MAPTRXFP1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL31406127 | 0.84 | LOXL2 (0.54) | MAPTRXFP1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL11806220 | 0.84 | LOXL2 (0.54) | MAPTRXFP1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL28264276 | 0.80 | ADORA1 (0.41) | MAPTRXFP1ALDH1A1KDM4EGAA | |
| SCHEMBL29991879 | 0.80 | GHSR (0.46) | KDM4EDAODDOTSHRCYP2C19 | |
| SCHEMBL16240933 | 0.80 | EGFR (0.52) | MAPTRXFP1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL25505982 | 0.79 | MAPT (0.53) | MAPTRXFP1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL31017907 | 0.79 | LOXL2 (0.73) | MAPTRXFP1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL27732761 | 0.78 | MAPT (0.39) | MAPTRXFP1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL30610463 | 0.77 | LOXL2 (0.60) | MAPTALDH1A1KDM4ELOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |