Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TPO | P07202 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LPO | P22079 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252222 | 0.86 | CYP2A6 (0.55) | ADORA1MAPTMEN1KMT2APKM | |
| SCHEMBL19329646 | 0.85 | MAPT (0.41) | MAPTMEN1KMT2APKMKDM4E | |
| SCHEMBL21026854 | 0.81 | MTNR1A (0.44) | MAPTMEN1KMT2APKMKDM4E | |
| SCHEMBL8591593 | 0.81 | MAPT (0.36) | MAPTMEN1KMT2APKMKDM4E | |
| SCHEMBL27475142 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL29991879 | 0.79 | GHSR (0.46) | KDM4EMTNR1AMTNR1BMPOTPO | |
| SCHEMBL6598876 | 0.78 | MAPT (0.51) | MAPTMEN1KMT2APKMKDM4E | |
| SCHEMBL27785513 | 0.78 | MAPT (0.40) | MAPTMEN1KMT2APKMKDM4E | |
| SCHEMBL13544012 | 0.78 | RAD52 (0.41) | MAPTMEN1KMT2APKMKDM4E | |
| SCHEMBL27978584 | 0.76 | CYP2A6 (0.51) | MAPTMEN1KMT2APKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997393-A | Two pyrrole amides of 6- fluorine boron-Benzazole compounds, preparation method and the method as fluorescence probe detection living cells multinucleation | 山东朱氏药业集团有限公司 | 2018-12-14 | — | — | CN | disclosed |