SCHEMBL27475154

SCHEMBL27475154

CCC(Cc1cncs1)C1(Br)CC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 16/20 0.33
SLC6A2 P23975 6/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27475526 0.69 SLC6A3 (0.32) SLC6A3
SCHEMBL5962368 0.68
SCHEMBL22356442 0.67 SLC6A3 (0.36) SLC6A3SLC6A2SLC6A4
SCHEMBL24924285 0.65
SCHEMBL27512089 0.65 HDAC8 (0.34) SLC6A3SLC6A2SLC6A4
SCHEMBL21117697 0.65 SLC6A3 (0.36) SLC6A3SLC6A2SLC6A4
SCHEMBL25487480 0.65 CTSK (0.39) SLC6A3SLC6A2
SCHEMBL25488068 0.62 LMNA (0.38) SLC6A3SLC6A2
SCHEMBL20470431 0.62 CTSK (0.42) SLC6A3SLC6A2SLC6A4
SCHEMBL6032061 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1173944-C Vitamin D-derivatives having a carbocyclic or heterocyclic substituent at C-25, method for the production thereof, intermediate products and use thereof for producing medicaments ���ֹɷݹ�˾ 2004-11-03 CN disclosed
CN-1216978-A Vitamin D-derivatives having a carbocyclic or heterocyclic substituent at C-25, method for the production thereof, intermediate products and use thereof for producing medicaments SCHERING AG (DE) 1999-05-19 CN disclosed