Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27585525 | 1.00 | MEN1 (0.42) | MEN1KMT2ACA12CA9RXFP1 | |
| Benzoic Acid SCHEMBL28206140 | 0.95 | DAO (0.42) | MEN1KMT2ACA12CA9RXFP1 | |
| SCHEMBL27673211 | 0.91 | MEN1 (0.49) | MEN1KMT2ACA12CA9KDM4E | |
| Bicarbonate SCHEMBL27933722 | 0.90 | TSHR (0.36) | MEN1KMT2ARXFP1TSHRKDM4E | |
| SCHEMBL27296444 | 0.89 | MEN1 (0.35) | MEN1KMT2ACA12CA9RXFP1 | |
| SCHEMBL28316156 | 0.89 | MKNK1 (0.38) | MEN1KMT2ACA12CA9RXFP1 | |
| Oxalic Acid SCHEMBL27401043 | 0.89 | CYP2C19 (0.35) | MEN1KMT2ATSHRKDM4ETDP1 | |
| Acetic Acid SCHEMBL663243 | 0.87 | CYP2C19 (0.40) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL28022926 | 0.87 | CYP3A4 (0.39) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| Benzene SCHEMBL19838142 | 0.87 | TSHR (0.41) | L3MBTL1TSHRKDM4EALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101198542-A | Product including carbon nano-tube and method for purifying fluid with the carbon nano-tube | SELTON TECHNOLOGY COMPANY (US) | 2008-06-11 | — | — | CN | claimed |
| CN-1933750-A | Layered high loft flame resistant batting, articles containing said batting, and processes for making same | DU PONT (US) | 2007-03-21 | — | — | CN | claimed |
| CN-216411815-U | Universal LCM fixed station foot | 杨朝志 | 2022-04-29 | — | — | CN | disclosed |
| CN-101933181-A | Sodium rechargeable battery | SUMITOMO CHEMICAL CO | 2010-12-29 | — | — | CN | disclosed |
| CN-101198542-A | Product including carbon nano-tube and method for purifying fluid with the carbon nano-tube | SELTON TECHNOLOGY COMPANY (US) | 2008-06-11 | — | — | CN | disclosed |
| CN-101187711-A | Wire grid polarizer | ROHM & HAAS DENMARK FINANCE AS (DK) | 2008-05-28 | — | — | CN | disclosed |
| CN-101174085-A | Nanostructured pattern method of manufacture | ROHM & HAAS DENMARK FINANCE AS (DK) | 2008-05-07 | — | — | CN | disclosed |
| CN-1922661-A | Etched dielectric film in hard disk drives | 3M INNOVATIVE PROPERTIES CO (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1146509-C | Tyre and method of making same | ��������̥��˾ | 2004-04-21 | — | — | CN | disclosed |
| CN-1328607-A | Geotextile fabric | BAY MILLS LTD (CA) | 2001-12-26 | — | — | CN | disclosed |
| CN-1325347-A | Tire and method for manufacturing the same | PIRELLI (IT) | 2001-12-05 | — | — | CN | disclosed |