Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27585525 | 0.95 | MEN1 (0.42) | DAOTSHRNAPRTMEN1KMT2A | |
| Terephthalic Acid SCHEMBL27475251 | 0.95 | MEN1 (0.42) | DAOTSHRNAPRTMEN1KMT2A | |
| Benzophenone SCHEMBL28929331 | 0.91 | ALDH1A1 (0.42) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| Bicarbonate SCHEMBL27933722 | 0.89 | TSHR (0.36) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| Oxalic Acid SCHEMBL27401043 | 0.87 | CYP2C19 (0.35) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL27673211 | 0.87 | MEN1 (0.49) | MEN1KMT2ACYP2D6CYP2C19SRD5A2 | |
| Acetic Acid SCHEMBL663243 | 0.86 | CYP2C19 (0.40) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL28022926 | 0.85 | CYP3A4 (0.39) | TSHRMEN1KMT2ACYP2D6CYP2C19 | |
| Benzene SCHEMBL19838142 | 0.85 | TSHR (0.41) | TSHRCYP2D6CYP2C19L3MBTL1CA1 | |
| Benzene SCHEMBL27434033 | 0.85 | TSHR (0.41) | TSHRCYP2D6CYP2C19L3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037590-B | Propylene impact copolymers and method | 格雷斯公司 | 2018-03-13 | — | — | CN | disclosed |